Electron microscopy Assessment of the kidneys from mice with cancer confirmed reversible pathological signs for example mesangial hypercellularity, though long term injury for example fibrosis or necrosis was not observed. Removal of NETs by therapy with DNase I, or pharmacological inhibition in the enzyme peptidylarginine deiminase 4 (PAD4), was sufficient https://wernerl898frc2.bmswiki.com/user