And lastly, clonidine boosts neuraxial opioids and, in combination with fentanyl, interacts in an additive manner, which may lessen the dose of each and every part by 60% for postoperative analgesia. Among the theories in regards to the mechanism of action of clonidine from the management of soreness inside https://www.proleviate.com/post/the-new-pain-killer-conolidine