Pentobarbital will lessen the level or impact of fosamprenavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. pentobarbital will decrease the extent or outcome of conivaptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Clients stabilized on corticosteroid therapy might have to have dosage adjustments if barbiturates are add... https://chaunceyb035ieb4.wikikali.com/user