Pentobarbital will decrease the extent or impact of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. pentobarbital will lower the level or influence of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. pentobarbital will decrease the extent or influence of bosentan by impacting hepatic enzyme CYP2C9/10 me... https://chelwoody841deg9.bimmwiki.com/user