In older people, this is important to comprehend as polypharmacy is frequent and might potentiate the potential risk of DDIs and ADRs. Therefore, concurrent ingestion of CYP2D6 inhibitors or inducers could potentiate or block tramadol conversion into ODT and This might raise or decrease efficacy/ADRs on the prescribed tramadol. https://o-dsmt-buy85061.wikigiogio.com/653411/o_dsmt_wiki_for_dummies